From powder to blister pack: the machines a tablet and capsule plant needs
A step-by-step guide to solid-dose manufacturing, the machine that does each job, and how to ask Jantrayan for a quotation.
A step-by-step guide to solid-dose manufacturing, the machine that does each job, and how to ask Jantrayan for a quotation.
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Step 1: Dispensing
A sensitive scale with a glass draft shield that weighs each ingredient exactly for the batch record.
Availability subject to feasibility check
Request this machineStep 1: Dispensing
A booth with filtered air flowing downwards, so powders can be weighed without dust reaching the operator or the room.
Availability subject to feasibility check
Request this machineStep 2: Granulation and drying
A bowl with a fast impeller and a chopper that mixes powders with a binder liquid into even, dense granules.
Availability subject to feasibility check
Request this machineStep 2: Granulation and drying
Blows warm air up through wet granules so they float and dry quickly and evenly, with filters to keep the powder in.
Availability subject to feasibility check
Request this machineStep 3: Blending
Turns a closed bin end over end, so the granules and other ingredients mix evenly without being opened to the room.
Availability subject to feasibility check
Request this machineStep 4: Tablet pressing or capsule filling
A turning table of punches and dies presses measured doses of granules into tablets, one after another.
Availability subject to feasibility check
Request this machineStep 4: Tablet pressing or capsule filling
Opens empty hard capsules, fills them with a measured dose of powder or pellets, and closes them again.
Availability subject to feasibility check
Request this machineStep 5: Coating
A perforated drum tumbles the tablets while a spray gun coats them evenly and warm air dries the coat.
Availability subject to feasibility check
Request this machineStep 6: Blister packing and cartoning
Forms pockets in plastic film, drops a tablet or capsule into each, and seals them with foil into strips.
Availability subject to feasibility check
Request this machineStep 6: Blister packing and cartoning
Opens flat cartons, puts in the strips and a leaflet, prints the batch details and closes each carton.
Availability subject to feasibility check
Request this machineStep 7: Quality control
Stirs tablets in vessels of warm liquid and samples it over time, to show how fast each tablet dissolves.
Availability subject to feasibility check
Request this machineStep 7: Quality control
Pumps a dissolved sample through a packed column and a detector to measure how much of each substance it contains.
Availability subject to feasibility check
Request this machineThe main steps in a solid-dose plant and the type of machine that usually does each one. Every step runs under the plant’s quality system.
Each raw material is weighed exactly for the batch in a clean, controlled area.
Machines at this step: Precision balance, Dispensing booth
Powders are mixed and bound into small granules, which are dried so they flow and press evenly.
Machines at this step: High-shear mixer granulator, Fluid bed dryer
Dried granules are blended with the remaining ingredients until every part of the batch is the same.
Machines at this step: Bin blender
The blend is pressed into tablets or filled into hard capsules, with weight checks along the way.
Machines at this step: Tablet press, Capsule filling machine
Many tablets get a thin coating that protects them, masks the taste or controls how they release.
Machines at this step: Tablet coating machine
Tablets and capsules are sealed into blister strips, which go into printed cartons with the leaflet.
Machines at this step: Blister packing machine, Cartoning machine
Samples from every batch are tested in the lab before the batch is released.
Machines at this step: Dissolution tester, Liquid chromatography (HPLC) system
See the machines that fill, seal, label and box products on a packing line.